IRLAB Therapeutics has announced top-line results from the Phase IIb REACT-PD study evaluating its second most clinically advanced asset, pirepemat, as a potential treatment for falls related to Parkinson’s disease (PF-Falls), a common comorbidity to the condition. The company has noted that, while the high-dose arm (600mg daily) reported a 42% reduction in falls over the 12-week study duration, the results were not statistically significant over the placebo arm. Moreover, while the high-dose arm indicated a meaningful improvement in cognitive impairment on the Montreal Cognitive Assessment scale, these results were also not statistically significant.
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